Stress Degradation Studies of Tebipenem and a Validated Stability-Indicating LC Method
نویسندگان
چکیده
منابع مشابه
Stress Degradation Studies of Tebipenem and a Validated Stability-Indicating LC Method
A inexpensive and rapid isocratic LC method has been developed for the quantitative determination of tebipenem-a new β-lactam antibiotic. Stress degradation studies were performed on tebipenem in acidic (0.2 N hydrochloric acid) and basic (0.02 N sodium hydroxide) solutions, in a solution with oxidizing agent (3 % hydrogen peroxide), and in the solid state, during thermolysis and photolysis. Fo...
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ژورنال
عنوان ژورنال: Chromatographia
سال: 2012
ISSN: 0009-5893,1612-1112
DOI: 10.1007/s10337-012-2331-4